Biotechnology and application of monoclonal antibodies in the diagnosis and treatment of diseases
-
Yegane Zahiri,1,* Roghayeh Gholizadeh Doran Mahalleh,2
1. Medical student, member of Young and Elite Researchers Club of Islamic Azad University, Zahedan, Iran
2. Department of laboratory sciences, Zahedan branch, Islamic Azad university, Zahedan, Iran
- Introduction: Monoclonal antibody biotechnology uses immune cells to make a special protein called an antibody. From this property and ability of B lymphocytes It is used to make specific antibodies called monoclonal antibodies because of the specificity of monoclonal antibodies as a powerful tool for detection the amount and position of a substance is used. The aim of biotechnology research is the application of monoclonal antibodies in the diagnosis and treatment of diseases.
- Methods: In this review study; Information on the use of monoclonal antibodies in the treatment of diseases from such databases
SCOPUS; SID; pubmed and magiran
Qualitative data analysis was performed.
- Results: Today Monoclonal antibodies are widely used in the diagnosis and identification of a large number of microbial infections. Also, because cancer cells are biochemically different from normal cells, we can make monoclonal antibodies that are specific to Cancer cells attach In addition to detecting human disease from monoclonal antibodies, a molecule with therapeutic potential can be isolated from a mixture of thousands of other molecules.
- Conclusion: we hope to use monoclonal antibodies in the treatment of cancer and other diseases. By attaching radioisotope material or a toxin to the anti-cancer monoclonal antibody, we can deliver the deadly substance to the cancer cell directly by shortening normal cells.
- Keywords: biotechnology ; antibody ; Monoclonal; Treatment and clinical medicine, diagnosis
